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Fingolimod (FTY720), a Sphinogosine-1-Phosphate Receptor Agonist, Mitigates Choroidal Endothelial Proangiogenic Properties and Choroidal Neovascularization

Neovascular or wet age-related macular degeneration (nAMD) causes vision loss due to inflammatory and vascular endothelial growth factor (VEGF)-driven neovascularization processes in the choroid. Due to the excess in VEGF levels associated with nAMD, anti-VEGF therapies are utilized for treatment. U...

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Detalles Bibliográficos
Autores principales: Sorenson, Christine M., Farnoodian, Mitra, Wang, Shoujian, Song, Yong-Seok, Darjatmoko, Soesiawati R., Polans, Arthur S., Sheibani, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946992/
https://www.ncbi.nlm.nih.gov/pubmed/35326420
http://dx.doi.org/10.3390/cells11060969