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Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy

Chimeric antigen receptor (CAR) T-cell therapies have shown impressive results in patients with hematological malignancies; however, little success has been achieved in the treatment of solid tumors. Recently, macrophages (MΦs) were identified as an additional candidate for the CAR approach, and ini...

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Detalles Bibliográficos
Autores principales: Paasch, Daniela, Meyer, Johann, Stamopoulou, Andriana, Lenz, Daniela, Kuehle, Johannes, Kloos, Doreen, Buchegger, Theresa, Holzinger, Astrid, Falk, Christine S., Kloth, Christina, von Kaisenberg, Constantin S., Abken, Hinrich, Schambach, Axel, Lachmann, Nico, Morgan, Michael, Moritz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947001/
https://www.ncbi.nlm.nih.gov/pubmed/35326445
http://dx.doi.org/10.3390/cells11060994