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Predation Stress Causes Excessive Aggression in Female Mice with Partial Genetic Inactivation of Tryptophan Hydroxylase-2: Evidence for Altered Myelination-Related Processes

The interaction between brain serotonin (5-HT) deficiency and environmental adversity may predispose females to excessive aggression. Specifically, complete inactivation of the gene encoding tryptophan hydroxylase-2 (Tph2) results in the absence of neuronal 5-HT synthesis and excessive aggressivenes...

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Detalles Bibliográficos
Autores principales: Svirin, Evgeniy, Veniaminova, Ekaterina, Costa-Nunes, João Pedro, Gorlova, Anna, Umriukhin, Aleksei, Kalueff, Allan V., Proshin, Andrey, Anthony, Daniel C., Nedorubov, Andrey, Tse, Anna Chung Kwan, Walitza, Susanne, Lim, Lee Wei, Lesch, Klaus-Peter, Strekalova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947002/
https://www.ncbi.nlm.nih.gov/pubmed/35326487
http://dx.doi.org/10.3390/cells11061036