Cargando…

Adrenomedullin and its receptors are expressed in mouse pancreatic β-cells and suppresses insulin synthesis and secretion

Gestational diabetes mellitus (GDM) is associated with defective pancreatic β-cell adaptation in pregnancy, but the underlying mechanism remains obscure. Our previous studies demonstrated that GDM women display increased plasma adrenomedullin (ADM) levels, and non-obese GDM mice show decreased serum...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Yuanlin, Ruano, Simone Hernandez, Mishra, Akansha, Pennington, Kathleen A., Yallampalli, Chandrasekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947024/
https://www.ncbi.nlm.nih.gov/pubmed/35324977
http://dx.doi.org/10.1371/journal.pone.0265890