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Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases

Background: Pulmonary hypertension (PH) is a life-threatening complication of connective tissue diseases (CTD); in this study, we aimed at investigating the potential role of inducible co-stimulator (ICOS) and its ligand (ICOS-L) as biomarkers of PH in CTD. Materials and Methods: We recruited 109 pa...

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Detalles Bibliográficos
Autores principales: Bellan, Mattia, Murano, Francesco, Ceruti, Federico, Piccinino, Cristina, Tonello, Stelvio, Minisini, Rosalba, Giubertoni, Ailia, Sola, Daniele, Pedrazzoli, Roberta, Maglione, Veronica, Manfredi, Giulia Francesca, Acquaviva, Antonio, Piffero, Roberto, Patti, Giuseppe, Pirisi, Mario, Sainaghi, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947069/
https://www.ncbi.nlm.nih.gov/pubmed/35328257
http://dx.doi.org/10.3390/diagnostics12030704