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Altered stability of nuclear lamin-B marks the onset of aging in male Drosophila

Epigenetic alterations occur during aging, but it remains unclear what epigenetic features are associated with the onset of physiological decline in animals. Nuclear lamin-B forms the filamentous meshwork underneath the nuclear envelope, providing the structural scaffold necessary for genome organiz...

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Detalles Bibliográficos
Autores principales: Lin, Wei-Qi, Ngian, Zhen-Kai, Koh, Tong-Wey, Ong, Chin-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947137/
https://www.ncbi.nlm.nih.gov/pubmed/35324942
http://dx.doi.org/10.1371/journal.pone.0265223