Cargando…
Altered stability of nuclear lamin-B marks the onset of aging in male Drosophila
Epigenetic alterations occur during aging, but it remains unclear what epigenetic features are associated with the onset of physiological decline in animals. Nuclear lamin-B forms the filamentous meshwork underneath the nuclear envelope, providing the structural scaffold necessary for genome organiz...
Autores principales: | Lin, Wei-Qi, Ngian, Zhen-Kai, Koh, Tong-Wey, Ong, Chin-Tong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947137/ https://www.ncbi.nlm.nih.gov/pubmed/35324942 http://dx.doi.org/10.1371/journal.pone.0265223 |
Ejemplares similares
-
NELF‐A controls Drosophila healthspan by regulating heat‐shock protein‐mediated cellular protection and heterochromatin maintenance
por: Ngian, Zhen‐Kai, et al.
Publicado: (2021) -
Increased intron retention is a post‐transcriptional signature associated with progressive aging and Alzheimer’s disease
por: Adusumalli, Swarnaseetha, et al.
Publicado: (2019) -
B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis in Drosophila male meiosis
por: Hayashi, Daisuke, et al.
Publicado: (2016) -
Truncated Tau caused by intron retention is enriched in Alzheimer’s disease cortex and exhibits altered biochemical properties
por: Ngian, Zhen-Kai, et al.
Publicado: (2022) -
Dynein pulling forces counteract lamin-mediated nuclear stability during nuclear envelope repair
por: Penfield, Lauren, et al.
Publicado: (2018)