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Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion

The mesoscale description of the subcellular organization informs about cellular mechanisms in disease state. However, applications of soft X-ray tomography (SXT), an important approach for characterizing organelle organization, are limited by labor-intensive manual segmentation. Here we report a pi...

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Detalles Bibliográficos
Autores principales: Li, Angdi, Zhang, Xiangyi, Singla, Jitin, White, Kate, Loconte, Valentina, Hu, Chuanyang, Zhang, Chuyu, Li, Shuailin, Li, Weimin, Francis, John Paul, Wang, Chenxi, Sali, Andrej, Sun, Liping, He, Xuming, Stevens, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947144/
https://www.ncbi.nlm.nih.gov/pubmed/35324950
http://dx.doi.org/10.1371/journal.pone.0265567