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Auto-segmentation and time-dependent systematic analysis of mesoscale cellular structure in β-cells during insulin secretion
The mesoscale description of the subcellular organization informs about cellular mechanisms in disease state. However, applications of soft X-ray tomography (SXT), an important approach for characterizing organelle organization, are limited by labor-intensive manual segmentation. Here we report a pi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947144/ https://www.ncbi.nlm.nih.gov/pubmed/35324950 http://dx.doi.org/10.1371/journal.pone.0265567 |