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Cooling Uncouples Differentially ROS Production from Respiration and Ca(2+) Homeostasis Dynamic in Brain and Heart Mitochondria
Hypothermia provides an effective neuro and cardio-protection in clinical settings implying ischemia/reperfusion injury (I/R). At the onset of reperfusion, succinate-induced reactive oxygen species (ROS) production, impaired oxidative phosphorylation (OXPHOS), and decreased Ca(2+) retention capacity...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947173/ https://www.ncbi.nlm.nih.gov/pubmed/35326440 http://dx.doi.org/10.3390/cells11060989 |