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Cooling Uncouples Differentially ROS Production from Respiration and Ca(2+) Homeostasis Dynamic in Brain and Heart Mitochondria

Hypothermia provides an effective neuro and cardio-protection in clinical settings implying ischemia/reperfusion injury (I/R). At the onset of reperfusion, succinate-induced reactive oxygen species (ROS) production, impaired oxidative phosphorylation (OXPHOS), and decreased Ca(2+) retention capacity...

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Detalles Bibliográficos
Autores principales: Stevic, Neven, Maalouf, Jennifer, Argaud, Laurent, Gallo-Bona, Noëlle, Lo Grasso, Mégane, Gouriou, Yves, Gomez, Ludovic, Crola Da Silva, Claire, Ferrera, René, Ovize, Michel, Cour, Martin, Bidaux, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947173/
https://www.ncbi.nlm.nih.gov/pubmed/35326440
http://dx.doi.org/10.3390/cells11060989