Evaluation of Ectopic Mitochondrial DNA in HeLa Cells

The presence of ectopic DNA in the cytoplasm induces inflammation and cell death. It has been widely reported that leakage of nuclear DNA into the cytoplasm can mainly be sensed by cyclic GMP-AMP synthase (cGAS). We recently reported that mitochondria-derived cytoplasmic double-stranded DNA (dsDNA)...

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Detalles Bibliográficos
Autores principales: Hussan, Mohammad T., Matsui, Noriko, Matsui, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947175/
https://www.ncbi.nlm.nih.gov/pubmed/35723303
http://dx.doi.org/10.3390/cimb44030080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947175/
https://www.ncbi.nlm.nih.gov/pubmed/35723303
http://dx.doi.org/10.3390/cimb44030080

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