Loss of Tpl2 activates compensatory signaling and resistance to EGFR/MET dual inhibition in v-RAS transduced keratinocytes

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer in the United States, affecting one million people per year. Patients with aggressive disease have limited treatment options and high mortality, highlighting the need to identify new biomarkers linked to poor clin...

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Detalles Bibliográficos
Autores principales: Kelley, Mary B., Geddes, Taylor J., Ochiai, Maria, Lampl, Noah M., Kothmann, W. Wade, Fierstein, Sara R., Kent, Victoria, DeCicco-Skinner, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947257/
https://www.ncbi.nlm.nih.gov/pubmed/35325006
http://dx.doi.org/10.1371/journal.pone.0266017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947257/
https://www.ncbi.nlm.nih.gov/pubmed/35325006
http://dx.doi.org/10.1371/journal.pone.0266017

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