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Multi-Design Differential Expression Profiling of COVID-19 Lung Autopsy Specimens Reveals Significantly Deregulated Inflammatory Pathways and SFTPC Impaired Transcription

The transcriptomic profiling of lung damage associated with SARS-CoV-2 infection may lead to the development of effective therapies to prevent COVID-19-related deaths. We selected a series of 21 autoptic lung samples, 14 of which had positive nasopharyngeal swabs for SARS-CoV-2 and a clinical diagno...

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Detalles Bibliográficos
Autores principales: Fassan, Matteo, Collesei, Antonio, Angerilli, Valentina, Sbaraglia, Marta, Fortarezza, Francesco, Pezzuto, Federica, De Gaspari, Monica, Businello, Gianluca, Moni, Margherita, Rizzo, Stefania, Traverso, Giulia, Colosso, Veronica, Taschin, Elisa, Lunardi, Francesca, Valls, Aida Freire, Schiavi, Francesca, Basso, Cristina, Calabrese, Fiorella, Dei Tos, Angelo Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947344/
https://www.ncbi.nlm.nih.gov/pubmed/35326463
http://dx.doi.org/10.3390/cells11061011