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Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
Proviral integration sites for Moloney murine leukemia virus (PIM) kinases are upregulated at the protein level in response to hypoxia and have multiple protumorigenic functions, promoting cell growth, survival, and angiogenesis. However, the mechanism responsible for the induction of PIM in hypoxia...
Autores principales: | Toth, Rachel K., Solomon, Regina, Warfel, Noel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947361/ https://www.ncbi.nlm.nih.gov/pubmed/35326457 http://dx.doi.org/10.3390/cells11061006 |
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