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The Selective Agonist for Sphingosine-1-Phosphate Receptors Siponimod Increases the Expression Level of NR4A Genes in Microglia Cell Line

Fingolimod (FTY720) and siponimod (BAF312) are selective agonists for sphingosine-1-phosphate (S1P) receptors approved for the treatment of relapsing–remitting (RR) and secondary progressive (SP) multiple sclerosis (MS), respectively. BAF312 exerts pro-myelination and neuro-protective functions on C...

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Detalles Bibliográficos
Autores principales: Montarolo, Francesca, Martire, Serena, Marnetto, Fabiana, Valentino, Paola, Valverde, Sabdi, Capobianco, Marco Alfonso, Bertolotto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947415/
https://www.ncbi.nlm.nih.gov/pubmed/35723306
http://dx.doi.org/10.3390/cimb44030083