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p53 Immunohistochemistry and Mutation Types Mismatching in High-Grade Serous Ovarian Cancer

High-grade serous carcinoma (HGSCa) of the ovary is featured by TP53 gene mutation. Missense or nonsense mutation types accompany most cases of HGSCa that correlate well with immunohistochemical (IHC) staining results—an all (missense) or none (nonsense) pattern. However, some IHCs produce subclonal...

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Detalles Bibliográficos
Autores principales: Park, Eunhyang, Han, Hyunho, Choi, Sung-Eun, Park, Hyunjin, Woo, Ha-Young, Jang, Mi, Shim, Hyo-Sup, Hwang, Sohyun, Kang, Haeyoun, Cho, Nam-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947437/
https://www.ncbi.nlm.nih.gov/pubmed/35328131
http://dx.doi.org/10.3390/diagnostics12030579