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Chimeric RNA Design Principles for RNA-Mediated Gene Fusion

One common genetic alteration in cancer is gene fusion resulting from chromosomal translocations. The mechanisms that create such oncogenic fusion genes are not well understood. Previously, we provided the direct evidence that expression of a designed chimeric RNA can drive the formation of TMPRSS2-...

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Detalles Bibliográficos
Autores principales: Gupta, Sachin Kumar, Yen, Laising
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947500/
https://www.ncbi.nlm.nih.gov/pubmed/35326453
http://dx.doi.org/10.3390/cells11061002