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Pilot Study of the Effects of Chronic Intracerebroventricular Infusion of Human Anti-IgLON5 Disease Antibodies in Mice

Background: Anti-IgLON5 disease is a rare late-onset neurological disease associated with autoantibodies against IgLON5, neuronal accumulation of phosphorylated Tau protein (p-Tau), and sleep, respiratory, and motor alterations. Purpose: We performed a pilot study of whether the neuropathological an...

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Detalles Bibliográficos
Autores principales: Alvente, Sara, Matteoli, Gabriele, Molina-Porcel, Laura, Landa, Jon, Alba, Mercedes, Bastianini, Stefano, Berteotti, Chiara, Graus, Francesc, Lo Martire, Viviana, Sabater, Lidia, Zoccoli, Giovanna, Silvani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947551/
https://www.ncbi.nlm.nih.gov/pubmed/35326477
http://dx.doi.org/10.3390/cells11061024