Protective Effect of Human-Neural-Crest-Derived Nasal Turbinate Stem Cells against Amyloid-β Neurotoxicity through Inhibition of Osteopontin in a Human Cerebral Organoid Model of Alzheimer’s Disease

The aim of this study was to validate the use of human brain organoids (hBOs) to investigate the therapeutic potential and mechanism of human-neural-crest-derived nasal turbinate stem cells (hNTSCs) in models of Alzheimer’s disease (AD). We generated hBOs from human induced pluripotent stem cells, i...

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Detalles Bibliográficos
Autores principales: Lim, Jung Yeon, Lee, Jung Eun, Park, Soon A, Park, Sang In, Yon, Jung-Min, Park, Jeong-Ah, Jeun, Sin-Soo, Kim, Seung Joon, Lee, Hong Jun, Kim, Sung Won, Yang, Seung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947560/
https://www.ncbi.nlm.nih.gov/pubmed/35326480
http://dx.doi.org/10.3390/cells11061029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947560/
https://www.ncbi.nlm.nih.gov/pubmed/35326480
http://dx.doi.org/10.3390/cells11061029

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