Mitochondrial Phenotypes in Genetically Diverse Neurodegenerative Diseases and Their Response to Mitofusin Activation

Mitochondrial fusion is essential to mitochondrial fitness and cellular health. Neurons of patients with genetic neurodegenerative diseases often exhibit mitochondrial fragmentation, reflecting an imbalance in mitochondrial fusion and fission (mitochondrial dysdynamism). Charcot–Marie–Tooth (CMT) di...

Descripción completa

Detalles Bibliográficos
Autores principales: Dang, Xiawei, Walton, Emily K., Zablocka, Barbara, Baloh, Robert H., Shy, Michael E., Dorn, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947610/
https://www.ncbi.nlm.nih.gov/pubmed/35326504
http://dx.doi.org/10.3390/cells11061053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947610/
https://www.ncbi.nlm.nih.gov/pubmed/35326504
http://dx.doi.org/10.3390/cells11061053

Ejemplares similares