Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration

Many neurons in the adult central nervous system, including retinal ganglion cells (RGCs), degenerate and die after injury. Early axon protein and organelle trafficking failure is a key component in many neurodegenerative disorders yet changes to axoplasmic transport in disease models have not been...

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Detalles Bibliográficos
Autores principales: Shah, Sahil H, Schiapparelli, Lucio M, Ma, Yuanhui, Yokota, Satoshi, Atkins, Melissa, Xia, Xin, Cameron, Evan G, Huang, Thanh, Saturday, Sarah, Sun, Catalina B, Knasel, Cara, Blackshaw, Seth, Yates, John R, Cline, Hollis T, Goldberg, Jeffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947766/
https://www.ncbi.nlm.nih.gov/pubmed/35259089
http://dx.doi.org/10.7554/eLife.68148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947766/
https://www.ncbi.nlm.nih.gov/pubmed/35259089
http://dx.doi.org/10.7554/eLife.68148

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