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CB2R Attenuates Intervertebral Disc Degeneration by Delaying Nucleus Pulposus Cell Senescence through AMPK/GSK3β Pathway

Nucleus pulposus (NP) cell (NPC) senescence is one of the main causes of intervertebral disc degeneration (IVDD). However, the underlying mechanism of NPC senescence is still unclear. The cannabinoid type 2 receptor (CB2R) is a member of the cannabinoid system and plays an important role in antioxid...

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Detalles Bibliográficos
Autores principales: Du, Jiacheng, Xu, Menglei, Kong, Fanchen, Zhu, Pengfei, Mao, Yubo, Liu, Yijie, Zhou, Hong, Dong, Zhongchen, Yu, Zilin, Du, Tong, Gu, Ye, Wu, Xiexing, Geng, Dechun, Mao, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947828/
https://www.ncbi.nlm.nih.gov/pubmed/35371598
http://dx.doi.org/10.14336/AD.2021.1025