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CB2R Attenuates Intervertebral Disc Degeneration by Delaying Nucleus Pulposus Cell Senescence through AMPK/GSK3β Pathway
Nucleus pulposus (NP) cell (NPC) senescence is one of the main causes of intervertebral disc degeneration (IVDD). However, the underlying mechanism of NPC senescence is still unclear. The cannabinoid type 2 receptor (CB2R) is a member of the cannabinoid system and plays an important role in antioxid...
Autores principales: | Du, Jiacheng, Xu, Menglei, Kong, Fanchen, Zhu, Pengfei, Mao, Yubo, Liu, Yijie, Zhou, Hong, Dong, Zhongchen, Yu, Zilin, Du, Tong, Gu, Ye, Wu, Xiexing, Geng, Dechun, Mao, Haiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8947828/ https://www.ncbi.nlm.nih.gov/pubmed/35371598 http://dx.doi.org/10.14336/AD.2021.1025 |
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