A functional variant of SHARPIN confers increased risk of late-onset Alzheimer’s disease

Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia, and its pathogenesis is multifactorial. We previously reported a rare functional variant of SHARPIN (rs572750141, NP_112236.3:p.Gly186Arg) that was significantly associated with LOAD. In addition, several recent studies have...

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Detalles Bibliográficos
Autores principales: Asanomi, Yuya, Shigemizu, Daichi, Akiyama, Shintaro, Miyashita, Akinori, Mitsumori, Risa, Hara, Norikazu, Ikeuchi, Takeshi, Niida, Shumpei, Ozaki, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948087/
https://www.ncbi.nlm.nih.gov/pubmed/34737388
http://dx.doi.org/10.1038/s10038-021-00987-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948087/
https://www.ncbi.nlm.nih.gov/pubmed/34737388
http://dx.doi.org/10.1038/s10038-021-00987-x

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