Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing

We report that overexpression of the m6A-demethylase alkB homolog 5 RNA demethylase (ALKBH5) promoted production of intron retention on the human papillomavirus type 16 (HPV16) E6 mRNAs thereby promoting E6 mRNA production. ALKBH5 also altered alternative splicing of the late L1 mRNA by an exon skip...

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Detalles Bibliográficos
Autores principales: Cui, Xiaoxu, Nilsson, Kersti, Kajitani, Naoko, Schwartz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948141/
https://www.ncbi.nlm.nih.gov/pubmed/35190939
http://dx.doi.org/10.1007/s11262-022-01889-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948141/
https://www.ncbi.nlm.nih.gov/pubmed/35190939
http://dx.doi.org/10.1007/s11262-022-01889-6

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