BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation

Helicobacter pylori causes gastric inflammation, gland hyperplasia and is linked to gastric cancer. Here, we studied the interplay between gastric epithelial stem cells and their stromal niche under homeostasis and upon H. pylori infection. We find that gastric epithelial stem cell differentiation i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapalczynska, Marta, Lin, Manqiang, Maertzdorf, Jeroen, Heuberger, Julian, Muellerke, Stefanie, Zuo, Xiangsheng, Vidal, Ramon, Shureiqi, Imad, Fischer, Anne-Sophie, Sauer, Sascha, Berger, Hilmar, Kidess, Evelyn, Mollenkopf, Hans-Joachim, Tacke, Frank, Meyer, Thomas F., Sigal, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948225/
https://www.ncbi.nlm.nih.gov/pubmed/35332152
http://dx.doi.org/10.1038/s41467-022-29176-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948225/
https://www.ncbi.nlm.nih.gov/pubmed/35332152
http://dx.doi.org/10.1038/s41467-022-29176-w

Ejemplares similares