The potential convergence of NLRP3 inflammasome, potassium, and dopamine mechanisms in Parkinson’s disease

The pathology of Parkinson’s disease (PD) is characterized by α-synuclein aggregation, microglia-mediated neuroinflammation, and dopaminergic neurodegeneration in the substantia nigra with collateral striatal dopamine signaling deficiency. Microglial NLRP3 inflammasome activation has been linked ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Pike, Adrianne F., Szabò, Ildikò, Veerhuis, Robert, Bubacco, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948240/
https://www.ncbi.nlm.nih.gov/pubmed/35332154
http://dx.doi.org/10.1038/s41531-022-00293-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948240/
https://www.ncbi.nlm.nih.gov/pubmed/35332154
http://dx.doi.org/10.1038/s41531-022-00293-z

Ejemplares similares