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The potential convergence of NLRP3 inflammasome, potassium, and dopamine mechanisms in Parkinson’s disease
The pathology of Parkinson’s disease (PD) is characterized by α-synuclein aggregation, microglia-mediated neuroinflammation, and dopaminergic neurodegeneration in the substantia nigra with collateral striatal dopamine signaling deficiency. Microglial NLRP3 inflammasome activation has been linked ind...
Autores principales: | Pike, Adrianne F., Szabò, Ildikò, Veerhuis, Robert, Bubacco, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948240/ https://www.ncbi.nlm.nih.gov/pubmed/35332154 http://dx.doi.org/10.1038/s41531-022-00293-z |
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