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Limited solvation of an electron donating tryptophan stabilizes a photoinduced charge-separated state in plant (6–4) photolyase

(6–4) Photolyases ((6–4) PLs) are ubiquitous photoenzymes that use the energy of sunlight to catalyze the repair of carcinogenic UV-induced DNA lesions, pyrimidine(6–4)pyrimidone photoproducts. To repair DNA, (6–4) PLs must first undergo so-called photoactivation, in which their excited flavin adeni...

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Detalles Bibliográficos
Autores principales: Hosokawa, Yuhei, Müller, Pavel, Kitoh-Nishioka, Hirotaka, Iwai, Shigenori, Yamamoto, Junpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948257/
https://www.ncbi.nlm.nih.gov/pubmed/35332186
http://dx.doi.org/10.1038/s41598-022-08928-0