Colorectal Cancer‐Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD‐L1 Expression in Tumor‐Associated Macrophages (Adv. Sci. 9/2022)

Small Extracellular Vesicles In colorectal cancer (CRC) tissues, tumor cell‐derived small extracellular vesicles (sEVs) miR‐21‐5p and miR‐200a synergistically induce macrophage M2 like polarization and PD‐L1 expression by regulating the PTEN/AKT and SCOS1/STAT1 pathways, resulting in decreased CD8(+...

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Detalles Bibliográficos
Autores principales: Yin, Yuan, Liu, Bingxin, Cao, Yulin, Yao, Surui, Liu, Yuhang, Jin, Guoying, Qin, Yan, Chen, Ying, Cui, Kaisa, Zhou, Leyuan, Bian, Zehua, Fei, Bojian, Huang, Shenglin, Huang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Inside Back Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948544/
http://dx.doi.org/10.1002/advs.202270057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948544/
http://dx.doi.org/10.1002/advs.202270057

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