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Mouse Modeling Dissecting Macrophage–Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis

Macrophage infiltration in mammary tumors is associated with enhanced tumor progression, metastasis, and poor clinical outcome, and considered as target for therapeutic intervention. By using different genetic mouse models, the authors show that ablation of the tyrosine kinase PYK2, either in breast...

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Detalles Bibliográficos
Autores principales: Müller, Anna‐Katharina, Köhler, Ulrike A., Trzebanski, Sébastien, Vinik, Yaron, Raj, Harsha Mohan, Girault, Jean‐Antoine, Ben‐Chetrit, Nir, Maraver, Antonio, Jung, Steffen, Lev, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948556/
https://www.ncbi.nlm.nih.gov/pubmed/35092356
http://dx.doi.org/10.1002/advs.202105696