Formulation of Chitosan-Coated Brigatinib Nanospanlastics: Optimization, Characterization, Stability Assessment and In-Vitro Cytotoxicity Activity against H-1975 Cell Lines

The purpose of the current study was to develop Brigatinib (BGT)-loaded nanospanlastics (BGT-loaded NSPs) (S1-S13) containing Span 60 with different edge activators (Tween 80 and Pluronic F127) and optimized based on the vesicle size, zeta potential (ZP), and percent entrapment efficiency (%EE) usin...

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Detalles Bibliográficos
Autores principales: Zaki, Randa Mohammed, Alfadhel, Munerah M., Alshahrani, Saad M., Alsaqr, Ahmed, Al-Kharashi, Layla A., Anwer, Md Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948618/
https://www.ncbi.nlm.nih.gov/pubmed/35337145
http://dx.doi.org/10.3390/ph15030348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948618/
https://www.ncbi.nlm.nih.gov/pubmed/35337145
http://dx.doi.org/10.3390/ph15030348

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