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The Inhibition of the Small-Conductance Ca(2+)-Activated Potassium Channels Decreases the Sinus Node Pacemaking during Beta-Adrenergic Activation
Sinus pacemaking is based on tight cooperation of intracellular Ca(2+) handling and surface membrane ion channels. An important player of this synergistic crosstalk could be the small-conductance Ca(2+)-activated K(+)-channel (I(SK)) that could contribute to the sinoatrial node (SAN) pacemaking driv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948633/ https://www.ncbi.nlm.nih.gov/pubmed/35337111 http://dx.doi.org/10.3390/ph15030313 |