Carajurin Induces Apoptosis in Leishmania amazonensis Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction

Carajurin is the main constituent of Arrabidaea chica species with reported anti-Leishmania activity. However, its mechanism of action has not been described. This study investigated the mechanisms of action of carajurin against promastigote forms of Leishmania amazonensis. Carajurin was effective a...

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Detalles Bibliográficos
Autores principales: Silva-Silva, João Victor, Moragas-Tellis, Carla J., Chagas, Maria S. S., Souza, Paulo Victor R., Moreira, Davyson L., Hardoim, Daiana J., Taniwaki, Noemi N., Costa, Vanessa F. A., Bertho, Alvaro L., Brondani, Daniela, Zapp, Eduardo, de Oliveira, Aldo Sena, Calabrese, Kátia S., Behrens, Maria D., Almeida-Souza, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948652/
https://www.ncbi.nlm.nih.gov/pubmed/35337130
http://dx.doi.org/10.3390/ph15030331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948652/
https://www.ncbi.nlm.nih.gov/pubmed/35337130
http://dx.doi.org/10.3390/ph15030331

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