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Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading

The relationship of lacunocanalicular network structure and mechanoresponse has not been well studied. The lacunocanalicular structures differed in the compression and tension sides, in the regions, and in genders in wild-type femoral cortical bone. The overexpression of Sp7 in osteoblasts resulted...

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Detalles Bibliográficos
Autores principales: Moriishi, Takeshi, Ito, Takuro, Fukuyama, Ryo, Qin, Xin, Komori, Hisato, Kaneko, Hitomi, Matsuo, Yuki, Yoshida, Noriaki, Komori, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948721/
https://www.ncbi.nlm.nih.gov/pubmed/35328592
http://dx.doi.org/10.3390/ijms23063173