Development and Optimization of CRISPR Prime Editing System in Photoautotrophic Cells

Prime editor (PE), a versatile editor that allows the insertion and deletion of arbitrary sequences, and all 12-point mutations without double-strand breaks (DSB) and a donor template, dramatically enhances research capabilities. PE combines nickase Cas9(H840A) and reverse transcriptase (RT), along...

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Detalles Bibliográficos
Autores principales: Jiang, Zhengzheng, , Abdullah, Zhang, Shun, Jiang, Yuli, Liu, Rui, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948812/
https://www.ncbi.nlm.nih.gov/pubmed/35335122
http://dx.doi.org/10.3390/molecules27061758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948812/
https://www.ncbi.nlm.nih.gov/pubmed/35335122
http://dx.doi.org/10.3390/molecules27061758

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