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Sex- and Genotype-Dependent Nicotine-Induced Behaviors in Adolescent Rats with a Human Polymorphism (rs2304297) in the 3′-UTR of the CHRNA6 Gene

In human adolescents, a single nucleotide polymorphism (SNP), rs2304297, in the 3′-UTR of the nicotinic receptor subunit gene, CHRNA6, has been associated with increased smoking. To study the effects of the human CHRNA6 3′-UTR SNP, our lab generated knock-in rodent lines with either C or G SNP allel...

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Detalles Bibliográficos
Autores principales: Cardenas, Anjelica, Bai, Yu, Hajy Heydary, Yasamin, Li, Jiaqi, Leslie, Frances M., Lotfipour, Shahrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948824/
https://www.ncbi.nlm.nih.gov/pubmed/35328565
http://dx.doi.org/10.3390/ijms23063145