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Inferring Time-Lagged Causality Using the Derivative of Single-Cell Expression

Many computational methods have been developed to infer causality among genes using cross-sectional gene expression data, such as single-cell RNA sequencing (scRNA-seq) data. However, due to the limitations of scRNA-seq technologies, time-lagged causal relationships may be missed by existing methods...

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Detalles Bibliográficos
Autores principales: Wei, Huanhuan, Lu, Hui, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948830/
https://www.ncbi.nlm.nih.gov/pubmed/35328768
http://dx.doi.org/10.3390/ijms23063348