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G-Quadruplex Matters in Tissue-Specific Tumorigenesis by BRCA1 Deficiency
How and why distinct genetic alterations, such as BRCA1 mutation, promote tumorigenesis in certain tissues, but not others, remain an important issue in cancer research. The underlying mechanisms may reveal tissue-specific therapeutic vulnerabilities. Although the roles of BRCA1, such as DNA damage...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948836/ https://www.ncbi.nlm.nih.gov/pubmed/35327946 http://dx.doi.org/10.3390/genes13030391 |