Effects of Injection Volume and Route of Administration on Dolutegravir In Situ Forming Implant Pharmacokinetics

Due to the versatility of the in situ forming implant (ISFI) drug delivery system, it is crucial to understand the effects of formulation parameters for clinical translation. We utilized ultrasound imaging and pharmacokinetics (PK) in mice to understand the impact of administration route, injection...

Descripción completa

Detalles Bibliográficos
Autores principales: Joiner, Jordan B., King, Jasmine L., Shrivastava, Roopali, Howard, Sarah Anne, Cottrell, Mackenzie L., Kashuba, Angela D. M., Dayton, Paul A., Benhabbour, Soumya Rahima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948873/
https://www.ncbi.nlm.nih.gov/pubmed/35335991
http://dx.doi.org/10.3390/pharmaceutics14030615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948873/
https://www.ncbi.nlm.nih.gov/pubmed/35335991
http://dx.doi.org/10.3390/pharmaceutics14030615

Ejemplares similares