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Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Ameliorated Insulin Resistance in Type 2 Diabetes Mellitus Rats

Human umbilical cord mesenchymal stem cell-derived small extracellular vesicle (hUC-MSCs-sEVs) therapy has shown promising results to treat diabetes mellitus in preclinical studies. However, the dosage of MSCs-sEVs in animal studies, up to 10 mg/kg, was considered high and may be impractical for fut...

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Detalles Bibliográficos
Autores principales: Yap, Seng Kar, Tan, Kian Leong, Abd Rahaman, Nor Yasmin, Saulol Hamid, Nur Fazila, Ooi, Der Jiun, Tor, Yin Sim, Daniel Looi, Qi Hao, Stella Tan, Li Kar, How, Chee Wun, Foo, Jhi Biau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948940/
https://www.ncbi.nlm.nih.gov/pubmed/35336023
http://dx.doi.org/10.3390/pharmaceutics14030649