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Molecular Analysis of L-Asparaginases for Clarification of the Mechanism of Action and Optimization of Pharmacological Functions

L-asparaginases (EC 3.5.1.1) are a family of enzymes that catalyze the hydrolysis of L-asparagine to L-aspartic acid and ammonia. These proteins with different biochemical, physicochemical and pharmacological properties are found in many organisms, including bacteria, fungi, algae, plants and mammal...

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Detalles Bibliográficos
Autores principales: Pokrovskaya, Marina V., Pokrovsky, Vadim S., Aleksandrova, Svetlana S., Sokolov, Nikolay N., Zhdanov, Dmitry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948990/
https://www.ncbi.nlm.nih.gov/pubmed/35335974
http://dx.doi.org/10.3390/pharmaceutics14030599