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Development, Statistical Optimization and Characterization of Fluvastatin Loaded Solid Lipid Nanoparticles: A 3(2) Factorial Design Approach

The purpose of the present research work was to design, optimize, and evaluate fluvastatin-loaded solid lipid nanoparticles (FLV-SLNPs) using 3(2) factorial design for enhancing the bioavailability. Fluvastatin has several disadvantages, including the low solubility and substantial first-pass metabo...

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Detalles Bibliográficos
Autores principales: Asif, Afzal Haq, Desu, Prasanna Kumar, Alavala, Rajasekhar Reddy, Rao, Gudhanti Siva Naga Koteswara, Sreeharsha, Nagaraja, Meravanige, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948994/
https://www.ncbi.nlm.nih.gov/pubmed/35335960
http://dx.doi.org/10.3390/pharmaceutics14030584