Cargando…

Development, Statistical Optimization and Characterization of Fluvastatin Loaded Solid Lipid Nanoparticles: A 3(2) Factorial Design Approach

The purpose of the present research work was to design, optimize, and evaluate fluvastatin-loaded solid lipid nanoparticles (FLV-SLNPs) using 3(2) factorial design for enhancing the bioavailability. Fluvastatin has several disadvantages, including the low solubility and substantial first-pass metabo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asif, Afzal Haq, Desu, Prasanna Kumar, Alavala, Rajasekhar Reddy, Rao, Gudhanti Siva Naga Koteswara, Sreeharsha, Nagaraja, Meravanige, Girish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8948994/ https://www.ncbi.nlm.nih.gov/pubmed/35335960 http://dx.doi.org/10.3390/pharmaceutics14030584

Ejemplares similares

Prevalence Study of Duchene Muscular Dystrophy and its Genetic Sequence in Southern India
por: SATTENAPALLI, Nigama Chandra, et al.
Publicado: (2023)

Non-Invasive Delivery of Nano-Emulsified Sesame Oil-Extract of Turmeric Attenuates Lung Inflammation
por: Rasool, Sahibzada Tasleem, et al.
Publicado: (2020)

Topical Nanoemulgel for the Treatment of Skin Cancer: Proof-of-Technology
por: Nagaraja, Sreeharsha, et al.
Publicado: (2021)

Enhancement of Anticorrosive Performance of Cardanol Based Polyurethane Coatings by Incorporating Magnetic Hydroxyapatite Nanoparticles
por: Asif, Afzal Haq, et al.
Publicado: (2022)

Ion-Triggered In Situ Gelling Nanoemulgel as a Platform for Nose-to-Brain Delivery of Small Lipophilic Molecules
por: Nagaraja, Sreeharsha, et al.
Publicado: (2021)

Study of Clinical Features and Diagnosis Pattern of Duchene Muscular Dystrophy in Southern India
por: Sattenapalli, Nigama Chandra, et al.
Publicado: (2022)

Therapeutic effects of Crataegus monogyna inhibitors against breast cancer
por: Basavarajappa, Girish Meravanige, et al.
Publicado: (2023)

Enantiospecific Pharmacogenomics of Fluvastatin
por: Hirvensalo, Päivi, et al.
Publicado: (2019)

The Race to Replace PDE5i: Recent Advances and Interventions to Treat or Manage Erectile Dysfunction: Evidence from Patent Landscape (2016–2021)
por: Islam, Mohammed Monirul, et al.
Publicado: (2022)

The Difference in Pharmacokinetics and Pharmacodynamics between Extended-Release Fluvastatin and Immediate-Release Fluvastatin in Healthy Chinese Subjects
por: Xu, H. R., et al.
Publicado: (2012)

An Approach to Enhance Dissolution Rate of Tamoxifen Citrate
por: SreeHarsha, Nagaraja, et al.
Publicado: (2019)

Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin
por: Lee, Chong-Ki, et al.
Publicado: (2013)

The Factory System and Factory Statistics
Publicado: (1837)

From seeds to survival rates: investigating Linum usitatissimum’s potential against ovarian cancer through network pharmacology
por: Islam, Mohammed Monirul, et al.
Publicado: (2023)

Kinetic Spectrophotometric Determination of Fluvastatin in Pharmaceutical Preparations
por: Ashour, Safwan, et al.
Publicado: (2010)

Green Synthesis and Characterization of Silver Nanoparticles of Psidium guajava Leaf Extract and Evaluation for Its Antidiabetic Activity
por: Nagaraja, Sreeharsha, et al.
Publicado: (2022)

1,5-Benzothiazepine Derivatives: Green Synthesis, In Silico and In Vitro Evaluation as Anticancer Agents
por: Haroun, Michelyne, et al.
Publicado: (2022)

Inhibition of Candida albicans by Fluvastatin Is Dependent on pH
por: Schmidt, Martin, et al.
Publicado: (2009)

Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
por: El-Helw, Abdel-Rahim M, et al.
Publicado: (2015)

Optimization of process parameters for fabrication of electrospun nanofibers containing neomycin sulfate and Malva sylvestris extract for a better diabetic wound healing
por: Monirul Islam, Mohammed, et al.
Publicado: (2022)

Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques
por: Almuqbil, Rashed M., et al.
Publicado: (2022)

Fluvastatin protects cochleae from damage by high-level noise
por: Richter, Claus-Peter, et al.
Publicado: (2018)

Enhanced oral bioavailability of fluvastatin by using nanosuspensions containing cyclodextrin
por: Li, Jun, et al.
Publicado: (2018)

Synergistic anti-tumor efficacy of sorafenib and fluvastatin in hepatocellular carcinoma
por: Cheng, Yang, et al.
Publicado: (2017)

Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy
por: Yang, Zuozhang, et al.
Publicado: (2017)

Fluvastatin Sodium Ameliorates Obesity through Brown Fat Activation
por: Yin, Na, et al.
Publicado: (2019)

Preventive effect of fluvastatin on the development of medication-related osteonecrosis of the jaw
por: Adachi, Naomi, et al.
Publicado: (2020)

Fluvastatin potentiates anticancer activity of vorinostat in renal cancer cells
por: Okubo, Kazuki, et al.
Publicado: (2019)

Efficacy of fluvastatin and aspirin for prevention of hormonally insensitive breast cancer
por: Bhardwaj, Anjana, et al.
Publicado: (2021)

Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer
por: Bhardwaj, Anjana, et al.
Publicado: (2022)

Enhancement of Anti-Tumoral Properties of Paclitaxel Nano-Crystals by Conjugation of Folic Acid to Pluronic F127: Formulation Optimization, In Vitro and In Vivo Study
por: Sreeharsha, Nagaraja, et al.
Publicado: (2022)

A spotlight on application of microwave-assisted modifications of plant derived polymers in designing novel drug delivery systems
por: Basavarajappa, Girish Meravanige, et al.
Publicado: (2023)

Fluvastatin Influences Hair Color in C57Bl/6 Mice
por: Galus, Ryszard, et al.
Publicado: (2013)

Hepatotoxicity Induced by Fluvastatin: A Reversible Acute Cholestatic Liver Injury
por: Alanazi, Najah S., et al.
Publicado: (2021)

Diversity of Solid Forms Promoted by Ball Milling: Characterization and Intrinsic Dissolution Studies of Pioglitazone Hydrochloride and Fluvastatin Sodium Drug–Drug Systems
por: Villeda-Villegas, Marco, et al.
Publicado: (2023)

Nonparametric statistical methods for complete and censored data
por: Desu, M M, et al.
Publicado: (2003)

Solid target for a neutrino factory
por: Skoro, G P, et al.
Publicado: (2010)

Solid Lipid Nanoparticles Embedded Hydrogels as a Promising Carrier for Retarding Irritation of Leflunomide
por: Alhelal, Hawra Mohammed, et al.
Publicado: (2023)

Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid
por: Silverman, S. L., et al.
Publicado: (2010)

Fluvastatin inhibits cardiomyocyte apoptosis after myocardial infarction through Toll pathway
por: Jia, Lili, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0vc27oiffd2ohnn24nt29en0lp