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Sevoflurane Effects on Neuronal Energy Metabolism Correlate with Activity States While Mitochondrial Function Remains Intact

During general anesthesia, alterations in neuronal metabolism may induce neurotoxicity and/or neuroprotection depending on the dose and type of the applied anesthetic. In this study, we investigate the effects of clinically relevant concentrations of sevoflurane (2% and 4%, i.e., 1 and 2 MAC) on dif...

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Detalles Bibliográficos
Autores principales: Maechler, Mathilde, Rösner, Jörg, Wallach, Iwona, Geiger, Joerg R. P., Spies, Claudia, Liotta, Agustin, Berndt, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949020/
https://www.ncbi.nlm.nih.gov/pubmed/35328453
http://dx.doi.org/10.3390/ijms23063037