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Development and Structural Analysis of Antibody Therapeutics for Filoviruses

The filoviruses, including ebolaviruses and marburgviruses, are among the world’s deadliest pathogens. As the only surface-exposed protein on mature virions, their glycoprotein GP is the focus of current therapeutic monoclonal antibody discovery efforts. With recent technological developments, poten...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoying, Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949092/
https://www.ncbi.nlm.nih.gov/pubmed/35335698
http://dx.doi.org/10.3390/pathogens11030374