Cargando…
Development and Structural Analysis of Antibody Therapeutics for Filoviruses
The filoviruses, including ebolaviruses and marburgviruses, are among the world’s deadliest pathogens. As the only surface-exposed protein on mature virions, their glycoprotein GP is the focus of current therapeutic monoclonal antibody discovery efforts. With recent technological developments, poten...
Autores principales: | Yu, Xiaoying, Saphire, Erica Ollmann |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949092/ https://www.ncbi.nlm.nih.gov/pubmed/35335698 http://dx.doi.org/10.3390/pathogens11030374 |
Ejemplares similares
-
Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment
por: Landeras-Bueno, Sara, et al.
Publicado: (2019) -
Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry
por: Schafer, Adam, et al.
Publicado: (2021) -
Filovirus Neutralising Antibodies: Mechanisms of Action and Therapeutic Application
por: Hargreaves, Alexander, et al.
Publicado: (2021) -
Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors
por: Bramble, Matthew S, et al.
Publicado: (2018) -
Aerosol Transmission of Filoviruses
por: Mekibib, Berhanu, et al.
Publicado: (2016)