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Bioactivity-Guided Separation of Anti-Cholinesterase Alkaloids from Uncaria rhynchophlly (Miq.) Miq. Ex Havil Based on HSCCC Coupled with Molecular Docking

As an important source of cholinesterase inhibitors, alkaloids in natural products have high potential value in terms of exerting pharmacological activities. In this study, a strategy for targeted preparation of cholinesterase inhibitors in Uncaria rhynchophlly (Miq.) Miq. ex Havil (UR) by high-spee...

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Detalles Bibliográficos
Autores principales: Yu, Pengfei, Chen, Zhenshan, Liu, Yuecheng, Gu, Zhengwei, Wang, Xiaoming, Zhang, Yaowen, Ma, Yanni, Dong, Meiyue, Tian, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949104/
https://www.ncbi.nlm.nih.gov/pubmed/35335376
http://dx.doi.org/10.3390/molecules27062013