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Genetic Diversity Does Not Contribute to Attenuation of HeLa Passaged Wild-Type Yellow Fever Virus Strain French Viscerotropic Virus

The disease yellow fever was prevented by two live attenuated vaccines, strains 17D and French neurotropic vaccine (FNV), derived by serial passage of wild-type (WT) strains Asibi and French Viscerotropic virus (FVV), respectively. Both 17D and FNV displayed decreased genetic diversity and resistanc...

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Detalles Bibliográficos
Autores principales: Strother, Ashley E., Thompson, Jill K., Widen, Steven G., Barrett, Alan D. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949127/
https://www.ncbi.nlm.nih.gov/pubmed/35336933
http://dx.doi.org/10.3390/v14030527