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Development and Optimization of Nanolipid-Based Formulation of Diclofenac Sodium: In Vitro Characterization and Preclinical Evaluation

In the present research study, we formulate bilosomes (BMs) of diclofenac (DC) for oral delivery for enhancement of therapeutic efficacy (anti-inflammatory disease). The BMS were prepared by thin film hydration method and optimized by Box–Behnken design (BBD) using cholesterol (A), lipid (B), surfac...

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Detalles Bibliográficos
Autores principales: Zafar, Ameeduzzafar, Alruwaili, Nabil K, Imam, Syed Sarim, Yasir, Mohd, Alsaidan, Omar Awad, Alquraini, Ali, Rawaf, Alenazy, Alsuwayt, Bader, Anwer, Md. Khalid, Alshehri, Sultan, Ghoneim, Mohammed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949207/
https://www.ncbi.nlm.nih.gov/pubmed/35335883
http://dx.doi.org/10.3390/pharmaceutics14030507