The miRNA-21-5p Payload in Exosomes from M2 Macrophages Drives Tumor Cell Aggression via PTEN/Akt Signaling in Renal Cell Carcinoma

M2 macrophages in the tumor microenvironment are important drivers of cancer metastasis. Exosomes play a critical role in the crosstalk between different cells by delivering microRNAs or other cargos. Whether exosomes derived from pro-tumorigenic M2 macrophages (M2-Exos) could modulate the metastati...

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Detalles Bibliográficos
Autores principales: Zhang, Zhicheng, Hu, Junhui, Ishihara, Moe, Sharrow, Allison C., Flora, Kailey, He, Yao, Wu, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949275/
https://www.ncbi.nlm.nih.gov/pubmed/35328425
http://dx.doi.org/10.3390/ijms23063005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949275/
https://www.ncbi.nlm.nih.gov/pubmed/35328425
http://dx.doi.org/10.3390/ijms23063005

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